Best CBD Oil Made in the USA

CBD (cannabidiol) has significantly risen in popularity over the several years, and with good reason. CBD occurs naturally in cannabis plants and the oil can be a really effective solution for several types of relief. CBD oil can help everything from anxiety to pain relief, sleeping disorders, stress reduction, and other issues that our bodies deal with on a day-to-day basis. So, we did the research to find out which manufacturers are making the best CBD oil in the USA. Typically, CBD is taken in one of two forms – drops (tinctures) or topical creams. We’ll focus on drops this time around. Our findings and the factors that went into our research are below. Let us know if you have any questions!

Our Findings

Overall, we found 6 American made CBD oil brands that really stood out from the competition, which was over 20 brands in total. In particular, we were really impressed by Spruce – a relative newcomer on the market that is great for all types of relief and helped me immediately cure my restless leg syndrome. We broke down our top picks into a few different categories: overall relief, full spectrum, flavored oils, THC free options, affordability, and product selections. Check out our recommendations below and everything else that we evaluated about each product.

Top Recommendations

Best CBD Oil Best for:
Spruce Overall Relief
Lazarus Naturals Most Affordable
Joy Organics THC Free
Green Roads Wide Product Selection
NuLeaf Naturals Full Spectrum
PureKana Flavored CBD Oil

Recommendations: Going Deeper

Below is deeper details on all of our top picks, along with what we liked, didn’t like, and where to get them.

Best for Overall Relief


Spruce is the best CBD oil we found in terms of overall relief and is a relatively newcomer onto the scene, founded in 2018. They work with two family-owned farms in Colorado and Kentucky to produce their 100% natural and pesticide-free CBD oil drops. Spruce drops come in two potency levels – 750 mg and 2400 mg for folks who need maximum strength relief. Along with their topical cream, Spruce runs these products through 3rd party, independent U.S. lab testing to make sure every batch is up to their quality standards, and they’ve never failed one of those tests for pesticides or other contaminants. For me, relief has been amazing with Spruce. I have restless leg syndrome and don’t sleep very well, but as soon as I started taking these drops, those issues immediately vanished. Mike uses it daily too. I’ve talked to several other Spruce customers as well that suffer from anxiety, chronic pain, and other issues, and they all say that Spruce helps them significantly with their daily struggles. Check out the other reviews on their site for yourself.

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Things we like:

  • Phenomenal relief
  • Won’t get you high, contains less than 0.3% THC
  • Third party lab tested
  • 100% natural and organic
  • Great customer service

Things we don’t like:

  • Lab test results aren’t available on their site, but can be provided upon request

Most Affordable

Lazarus Naturals

Lazarus Naturals is a good option for people who need an effective product but are a bit price conscious. The only downside that we could see for their CBD oil drops is the time to full effect, which can be up to a couple of hours after you take your dose. Typically, we like to see that time under an hour if you’re taking the right dosage. However, that’s not to take away from the quality ingredients that go into this product. Lazarus Naturals oil is made with full spectrum hemp extract and contains 50 mg of CBD per 1 ml (essentially 1.6 mg per drop). It’s vegan, gluten free, and doesn’t have any preservatives or other harmful chemicals in it. In terms of relief, we saw similar results from this product compared to others we researched, it just took a bit longer to take effect. Final watch out – don’t take this if you’re allergic to tree nuts since it contains coconut oil.

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Things we like:

  • Effective relief
  • Full spectrum
  • Vegan and gluten free

Things we don’t like:

  • Longer full effect time than average
  • Contains tree nuts, which is a common allergy

Best THC Free CBD Oil

Joy Organics

Joy Organics is a really cool company that has a focus on giving back to the community while also making some great CBD products. Their CBD oil tinctures come in 4 dosages and 4 flavors: mint, orange, lemon, and non-flavored. The thing we really love most about Joy Organics though is their transparency of product information – they list just about everything, from microbial analysis to contaminant analysis and a full ingredients label. They even have a dedicated page that lays out their entire production process in detail. Overall, this is a great product that is THC free, lab tested, kosher, organic, and provided relief for a lot of people.

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Things we like:

  • Transparent lab test results
  • Kosher and organic
  • Several flavor and potency options
  • Free shipping anywhere in the U.S.

Things we don’t like:

  • None

Best for Wide Product Selection

Green Roads

Green Roads has a massive CBD product selection that can be a bit overwhelming, but they do a good job of laying out all of the information about their products so you can make a good decision on what’s right for you. In addition to their drops, they also offer edibles, capsules, topical creams, and other CBD varieties. Our recommendation is their 50 mg/ML CBD oil, which has good lab test results and should be effective for several types of relief in most people (everyone is different, however). For every single batch of their CBD tinctures, they link to the exact lab sheet results right from their product pages. They also list a ton of great information around compliance, safety, and answer frequently asked questions about each product. In terms of relief, Green Roads has done a good job of solving a lot of different issues from arthritis to anxiety and others.

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Things we like:

  • Good relief
  • Easy to find lab test results
  • Specific dosage recommendations
  • Wide product selection

Things we don’t like:

  • None

Other Full Spectrum CBD Oil We Liked

NuLeaf Naturals

NuLeaf Naturals has been around since 2014 and get all of their CBD products from therapeutic hemp plants grown on licensed farms in Colorado. Similar to other products we liked, NuLeaf tinctures are whole-plant extracts, meaning they occur naturally and aren’t synthetic. These drops come in containers from 240 mg to all the way to 4850 mg and contain about 50mg cannabinoids per milliliter of oil. It’s also non-GMO and 100% organic – zero pesticides or other nasty chemicals that could potentially have harmful side effects. NuLeaf drops work well too for several types of relief – we’ve talked to folks first-hand about the benefits they’ve seen with everything from anxiety to pain relief, even in pets. Overall, very good full spectrum product that is worth trying if you haven’t found the CBD oil that works for you yet.

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Things we like:

  • Non-GMO and 100% organic
  • Seen it help with several types of both mental and physical relief
  • Lots of size options for various dosage needs
  • Quick customer service

Things we don’t like:

  • Very earthy flavor which can bother some people

Best Flavored CBD Oil


The vanilla flavored CBD oil from PureKana was the best one we found for people who don’t want the earthy, raw hemp taste. To get the subtle vanilla flavor, they incorporate vanilla extract from organic V. planifolia plants during the infusion process. In terms of potency, this product comes in 300 mg, 600 mg, and 1000 mg bottles. Similar to NuLeaf, PureKana is non-GMO and 100% organic with no pesticides or herbicides to be found. It’s also non-psychoactive, although isn’t fully void of THC, containing less than .02% typically. We’ve seen great pain relief results from this product for mental and physical ailments, although it may just take some testing to figure out the right dosage for you. We found ourselves wanting more information about lab test results and other specifics outside of their ingredients label, which made it tough to determine the right dosage and had us playing trial and error a bit.

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Things we like:

  • Great flavor
  • No harmful chemicals
  • Good relief results
  • Fast customer service

Things we don’t like:

  • Lack of lab results transparency on their site

Recap: Best CBD Oil Drops Made in the USA

Factors We Considered


First and foremost, we measured effectiveness of each product when it comes to relief of all types, including:

  • Sleep issues
  • Anxiety
  • Stress
  • Joint pain relief
  • Muscle pain relief
  • Other types of pain

Note, effectiveness varies widely based on the person and the condition that you’re looking to relieve. We selected products that had a high effectiveness rate across a wide variety of use cases.


There are a bunch of different potency levels and concentrations for CBD products out there. Strengths typically range from 200 mg to over 2,000 mg, and the potency that is right for you varies by person. Everyone’s biological makeup is different, so what is right for your friend may not be the right dosage for you. We tried to include brands that offer a wide range of strengths so you can pick the right one for your situation. If you’re a beginner, start off with a low potency to see how you react and then work your way up.


Unfortunately, there are some CBD oil producers out there that have little regard for consumer safety. Since it’s not an industry that is as tightly regulated as others by the government, you really have to pay attention to the ingredients list of the products you’re looking to buy to make sure there aren’t any harmful chemicals or pesticides in them. Here are some of the harmful chemicals to look out for:

  • Myclobutanil
  • Bifenazate
  • Dextromethorphan

Test Results

We really valued when brands listed lab test results alongside their products, preferably from a third party. These results help verify the quality of their CBD oil and go a long way creating transparency between brands and consumers. In the lab results, we specifically looked at the cannabinoid and terpene profiles of each product strain. The more transparency here, the better.

Side Effects

We looked for tinctures that resulted in minimal to zero side effects. Some brands will have more THC in them than others, which can cause a psychoactive high, given a large enough dose. We made sure to only include brands that didn’t cause that side effect, along with others like vitro cell viability or decreased fertilization capacity.

Customer Service

It’s natural that you have a lot of questions when it comes to products to help improve your health. So, fast and reliable customer service was super important to us when evaluating companies. We looked at a few different aspects here:

  • Responsiveness to live chat or contact form submissions
  • Helpfulness over email and phone
  • Seamless and clear ordering process
  • Fast shipping times and good policies


We always want to make sure you’re getting the best bang for your buck, so cost is always a consideration. We weighed the quality of each product against the cost and eliminated several brands where we felt like their product quality just didn’t live up to the price tag. We also really liked brands that give discounts to customers who sign up for regular subscriptions.

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